Physical Fitness, Exercise Capacity and Activities of Daily Living in Primary Ciliary Dyskinesia: a Retrospective Study

Hacettepe University

Status: Completed

Conditions: Kartagener Syndrome; Primary Ciliary Dyskinesia; Immotile Cilia Syndrome

Treatments: Other: Data Collection

Study type: Observational

Funder types: Other

Identifiers

NCT05040607

GO 19/730

Details and patient eligibility

About

Decreased pulmonary function, peripheral muscle strength, and exercise capacity were reported in primary ciliary dyskinesia (PCD) in recent studies. We aimed to investigate the data conducted between 10 July 2015 and 10 January 2015 of pulmonary function, respiratory muscle strength, exercise capacity, physical fitness, and activities of daily living (ADL) in PCD and healthy counterparts retrospectively at the first stage of the study and the effects of inspiratory muscle training on pulmonary function, respiratory muscle strength, and exercise capacity in PCD patients with decreased inspiratory muscle strength from the database recorded between 10 July 2015 and 10 January 2015 retrospectively at the second stage of the study.

Enrollment: 48 patients

Sex: All

Ages: 8 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinically stable
• Being able to cooperate with the assessments
• Not having any orthopedic, or neurological problems

Exclusion criteria

• Not being clinically stable
• Not being able to cooperate with the assessments
• Having any orthopedic, or neurological problems

Trial design

48 participants in 2 patient groups

Primary Ciliary Dyskinesia (PCD)

Description:

The first stage of the study: Data of 20 PCD patients from the database recorded between 10 July 2015 and 10 January 2017. The second stage of the study: -Data of 14 PCD patients who had lower inspiratory muscle strength from the same database underwent supervised inspiratory muscle training (IMT) with tapered flow resistive loading using Powerbreathe K5 device at our research unit and airway clearance techniques (ACT) as a home-based therapy for 6 weeks from the database recorded between 10 July 2015 and 10 January 2017.

Treatment:

Other: Data Collection

Other: Data Collection

Healthy Group

Description:

Data of 20 healthy subjects from the database recorded between 10 July 2015 and 10 January 2017.

Treatment:

Other: Data Collection

Other: Data Collection