Physical Rehabilitation and Chronic Kidney Disease (IMPREPA)

Civil Hospices of Lyon

Status: Unknown

Conditions: Chronic Kidney Disease; Older; Sarcopenia

Treatments: Behavioral: Physical rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT03671343

69HCL17_0598

Details and patient eligibility

About

Older patients with chronic renal failure suffer from sarcopenia. Loss of muscle function is associated with increased morbidity and mortality. Currently few treatment are available. The aim of this study is to evaluate the impact of physical rehabilitation in this population on muscle performance and quality of life.

Enrollment: 90 estimated patients

Sex: All

Ages: 70+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• man or woman
• age over 70 years
• CKD stage 3B, 4 or 5 or a DFG <45ml / min according to CKD-EPI formula
• an SPPB (Short Physical Performance Battery test )<10
• having received a complete and loyal information and having given his written and informed consent.
• ability to rehabilitate

Exclusion criteria

• Subject not presenting previous inclusion criteria
• General condition not compatible for the realization of physical rehabilitation
• Patient protected under the terms of the law.
• Inability to respect the follow-up of the study for geographical, social or psychological reasons.
• depression or other psychiatric disorder
• Refusal to participate in the study
• Absence of affiliation to the social security system
• Subject in a exclusion period of an other study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 2 patient groups

Intervention : Physical rehabilitation

Experimental group

Description:

The Arm "Physical rehabilitation" will benefit from the implementation of the "Loss of Mobility Prevention" program set up in the Department of Aging Medicine of the Center Hospitalier Lyon Sud (CHLS) of Pr BONNEFOY.

Treatment:

Behavioral: Physical rehabilitation

Control : optimized medical treatment

No Intervention group

Description:

The Arm "Optimized medical treatment" will not benefit from the implementation of the "Loss of Mobility Prevention" program.