Physical Training During Hospital Admission With Community-Acquired Pneumonia

Nordsjaellands Hospital

Status: Unknown

Conditions: Community-acquired Pneumonia

Treatments: Behavioral: In-bed cycling; Behavioral: Exercise booklet

Study type: Interventional

Funder types: Other

Identifiers

NCT04094636

CAP-EX

Details and patient eligibility

About

The purpose of this study is to assess the effect of standard usual care combined with daily supervised physical training during hospitalization with community-acquired pneumonia (CAP) compared to standard usual care alnone.

Full description

Community-acuired pneumonia (CAP) is a leading cause of hospitalization worldwide. Despite increased focus on mobilization, hospitalization is associated with bed rest. Bed rest with low levels of physical activity leads to functional deline as well as increased risk of complications.

This study is a randomized controlled trial, which investigates the effect of standard usual care combined with daily supervised physical training in patients hospitalized with CAP compared to standard usual care alone.

Enrollment: 210 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients 18 years of age or older admitted to hospital with CAP defined as a new infiltrate on chest X-ray/CT and minimum one of the following symptoms: temperature <35˚C or ≥38˚C, cough, pleuritic chest pain, dyspnea, or focal chest signs on auscultation.
• Patients should have an expected admission length of ≥72 hours.
• Patients should be able to move their legs.

Exclusion criteria

• Patients unable to give written consent.
• Hospital admission within the last 14 days.
• Severe immunosuppression (cancer chemotherapy ≤28 days, neutropenia ≤1000 cells/μL, ≥20 mg prednisolone-equivalent/day >14 days or other immunosuppressive drugs, HIV infection, former transplant).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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210 participants in 3 patient groups

No intervention: Control

No Intervention group

Description:

Control group

In-bed cycling

Experimental group

Description:

Supervised in-bed cycling

Treatment:

Behavioral: In-bed cycling

Exercise booklet

Experimental group

Description:

Supervised physical training with exercises from exercise booklet

Treatment:

Behavioral: Exercise booklet