Physical Training in Patients With Idiopathic Inflammatory Myopathies

University of Sao Paulo

Status: Completed

Conditions: Physical Activity; Idiopathic Inflammatory Myopathies

Treatments: Other: Physical exercises

Study type: Interventional

Funder types: Other

Identifiers

NCT03092167

MYO-HCFMUSP-02

Details and patient eligibility

About

Physical training may improve physical capacity and health parameters in various systemic autoimmune diseases, including idiopathic inflammatory myopathies. Therefore, the present study will assess the role of an exercise training program in patients with idiopathic inflammatory myopathies.

Full description

To assess the impact of 12-weeks of physical training in patients with idiopathic inflammatory myopathies.

Enrollment: 12 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diagnosis of DM / PM according to the criteria of Bohan and Peter (1975)
• Both genders and age ≥ 18 years
• Use of prednisone ≤ 0.5 mg/kg/day in the last three months. The dose of prednisone will be kept fixed throughout the study
• Physically inactive

Exclusion criteria

• Disease relapsing
• Neoplasia associated-myositis
• Overlapping myositis
• Use of lipid-lowering drugs
• Smoking
• Diabetes mellitus

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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12 participants in 3 patient groups

Case

Active Comparator group

Description:

Patients: this group will be submitted to 12-weeks, twice/week, physical exercises.

Treatment:

Other: Physical exercises

Control

No Intervention group

Description:

Patients: this group will not be submitted to 12-weeks, twice/week, physical exercises.

Healthy control

No Intervention group

Description:

Volunteers: this group will not be submitted to 12-weeks, twice/week, physical exercises.