Physician and Patient Perception of Adjustable Maintenance Dosing of Symbicort Turbuhaler (REALITY)

AstraZeneca

Status: Completed

Conditions: Perception of Physicians & Patients of AMD

Treatments: Drug: Symbicort

Study type: Observational

Funder types: Industry

Identifiers

NCT00812682

D5890L00021

Details and patient eligibility

About

This study will evaluate the perception of the physicians and the patients about the approved adjustable dosing of Symbicort® 160/4,5. Symbicort maintenance dose will be adjusted up and down within the approved dose range of 1x2 - 4x2 inhalations per day, to the level of asthma symptoms. Patients and physicians perception of this new dosing schedule will be evaluated by means of questionnaires completion and direct questioning.

Enrollment: 217 patients

Sex: All

Ages: 12+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Minimum of 6 months history of asthma and treatment with an inhaled corticosteroids for at least 3 months prior to visit 1 and/or a history of short term variation in airway function and asthma symptoms responding promptly to convent
• Patients where use of a combination (inhaled corticosteroid and long acting beta2-agonist is appropriate, i.e. not controlled on inhaled corticosteroids alone).

Exclusion criteria

• Asthma exacerbation requiring oral corticosteroid treatment in the four weeks prior to visit 1
• Upper Respiratory Tract Infection in the previous four weeks
• Severe cardiovascular disease or other significant concomitant disease, which may interfere with the conduct of the study.
• Women enrolled in the trial should not be planning pregnancy and should be taking adequate contraceptive measures where appropriate.
• Previous enrollment in a clinical study
• Known or suspected hypersensitivity to budesonide, formoterol or inhaled lactose