Physiologic Effects of CPAP After Vascular Surgery (PhyCUS)

University of Genova

Status: Unknown

Conditions: Postoperative Complications; Respiratory Failure

Treatments: Device: Postoperative preventive CPAP

Study type: Observational

Funder types: Other

Identifiers

NCT03543930

PhyCUS Study

Details and patient eligibility

About

This study aims to investigate, with a case-crossover design, the effects of a short course of preventive CPAP administered in the immediate postoperative period in patients at high-risk of developing postoperative pulmonary complications undergoing major vascular surgery.

Enrollment: 18 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Open or endovascular surgery on the abdominal aorta
• Surgical procedure requiring general anaesthesia and invasive intraoperative mechanical ventilation
• Intermediate-high risk of postoperative pulmonary complications (ARISCAT score ≥ 26)

Exclusion criteria

• Prolonged post-operative invasive ventilation
• Invasive or non-invasive ventilation or oxygen therapy in the last month
• ASA class IV or V
• Emergency procedures
• Pneumothorax or active pulmonary infection
• Any contraindication to CPAP
• Prolonged bed rest
• Patient refusal to participate or to receive preventive CPAP

Trial design

18 participants in 2 patient groups

Major open vascular surgery

Description:

Surgical procedures on the abdominal aorta requiring median abdominal incision

Treatment:

Device: Postoperative preventive CPAP

Endovascular aortic repair

Description:

Abdominal aortic repair with endovascular approach

Treatment:

Device: Postoperative preventive CPAP