Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly

US Department of Veterans Affairs (VA)

Status and phase: Completed; Phase 4

Conditions: Muscle Weakness; Muscular Atrophy

Treatments: Procedure: exercise; Drug: testosterone

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT00018356

AGCG-007-98S

Details and patient eligibility

About

This study's primary objective is to determine the independent and combined effects of progressive resistance muscle strength training and testosterone on the development of sustainable improvements in physical function.

Enrollment: 88 estimated patients

Sex: Male

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

The study will be limited to those patients who are metabolically stable and free of metastatic cancer and limiting end organ disease. Their total serum testosterone must be less than 480 and PSA less than 10.

Exclusion Criteria:

Trial design

88 participants in 1 patient group

1

Other group

Treatment:

Procedure: exercise

Drug: testosterone