Physiologic Evaluation of Anomalous Right Coronary Artery Stenosis

Seoul National University

Status and phase: Completed; Phase 4

Conditions: Coronary Vessel Anomalies

Treatments: Procedure: revascularization

Study type: Interventional

Funder types: Other

Identifiers

NCT01133054

D-0908-010-060

Details and patient eligibility

About

The anomalous origin of right coronary artery (RCA) is a rare coronary anomaly. Recently, the detection of this anomaly has been more frequent as the use of cardiac multidetector computed tomography has become more popular. It can cause myocardial ischemia, syncope and sudden cardiac death. Surgical repair is generally recommended for symptomatic patients. However, there is controversy concerning the proper evaluation and treatment strategy for patients without documented myocardial ischemia.

The stenotic lesion of anomalous origin of RCA will be assessed by fractional flow reserve (FFR).

Enrollment: 36 patients

Sex: All

Ages: 20 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients diagnosed as anomalous origin of right coronary artery from left coronary cusp

Exclusion criteria

• poor compliance
• need for percutaneous coronary intervention to significant coronary lesion
• failure of FFR for anomalous origin of right coronary artery

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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36 participants in 2 patient groups

low FFR

Experimental group

Description:

FFR\<0.75

Treatment:

Procedure: revascularization

high FFR

No Intervention group

Description:

FFR \> 0.75