Physiologic Performance Response to Salbutamol

University of Copenhagen

Status: Unknown

Conditions: Healthy

Treatments: Drug: Placebo; Drug: salbutamol

Study type: Interventional

Funder types: Other

Identifiers

NCT04615611

SAL-POWER

Details and patient eligibility

About

This project aims to investigate the individual physiological response to beta2-adrenergic stimulation with salbutamol on performance-related outcomes

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 to 45 years of age
• Trained individuals with maximal oxygen uptake above 55 mL/kg/min for men and 50 mL/kg/min for women
• Body mass index lower than 26

Exclusion criteria

• Allergy towards study drug
• Unacceptable side effects of the study drug
• Chronic disease deemed by the MD to impose a risk or severely confound the study outcomes
• Current smokers
• Use of prescription medicine
• Pregnancy

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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20 participants in 2 patient groups, including a placebo group

salbutamol

Experimental group

Description:

salbutamol, 800 microgram from metered dose inhaler

Treatment:

Drug: salbutamol

placebo

Placebo Comparator group

Description:

placebo

Treatment:

Drug: Placebo