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Physiological Adaptations to Simulated Intermittent Altitude on Human Health and Performance

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Mayo Clinic

Status

Completed

Conditions

Altitude Hypoxia

Treatments

Other: Simulated altitude
Other: Placebo simulated altitude

Study type

Interventional

Funder types

Other

Identifiers

NCT03743610
18-000484 (Other Identifier)

Details and patient eligibility

About

The investigators expect to find that different intensity and altitude exposure levels will show what kind of intermittent exposure protocol is more beneficial to athletes and healthy individuals that experience acute exposure to altitude during exercise. This may furthermore be related to acute altitude exposure for recreational exercise use as well.

Enrollment

71 patients

Sex

All

Ages

18 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • 18-70 years of age,
  • history of good health,
  • generally active to competitive athletes.

Exclusion criteria

  • History of cardiac or pulmonary disease,
  • not currently active,
  • unable to exercise or meet study requirements (e.g., number of sessions),
  • live at altitude (>2,100m or 7,000ft).

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

71 participants in 4 patient groups, including a placebo group

Effect of heart rate training in simulated altitude
Experimental group
Description:
Participants will exercise in simulated altitude start at a minimum of 2,000ft and will increase to no greater than 16,400ft with each visit. The increase will be in accordance to maintaining \>65% max heart rate during room air based maximal peak work.
Treatment:
Other: Simulated altitude
Effect of saturation of oxygen training in simulated altitude
Experimental group
Description:
Participants will exercise in simulated altitude start at a minimum of 2,000ft and will increase to no greater than 16,400ft with each visit. The increase will be in accordance to maintaining 40-60% of max work rate during room air work rate and based upon saturation of oxygen of between 70-80%.
Treatment:
Other: Simulated altitude
Effect of optimized training in simulated altitude
Active Comparator group
Description:
Participants will perform the more beneficial intervention (heart rate or saturation of oxygen training) to evaluate whether it improves elite athlete's training status at altitude.
Treatment:
Other: Simulated altitude
Effect of placebo training in non-simulated altitude
Placebo Comparator group
Description:
Participants will perform placebo beneficial intervention (heart rate or saturation of oxygen training) to evaluate whether the optimized protocol truely improves elite athlete's training status at altitude.
Treatment:
Other: Placebo simulated altitude

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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