Physiological Changes With SPG Stimulation in Migraine Patients

Danish Headache Center

Status: Completed

Conditions: Chronic Migraine

Treatments: Device: Sham stimulation; Device: Neurostimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT02510742

H-1-2011-152

Details and patient eligibility

About

Hypothesis:

Stimulation of the SPG at low frequencies (20 Hz)is believed to cause a physiological parasympathetic upregulation which increases VMCA, concentration and cephalic vessel diameter.

Enrollment: 12 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chronic migraine patients

Exclusion criteria

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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12 participants in 2 patient groups

SPG neurostimulation

Active Comparator group

Description:

SPG neurostimulation of frequency 20 Hz

Treatment:

Device: Neurostimulation

Control

Sham Comparator group

Description:

Sham neurostimulation of amplitude=0

Treatment:

Device: Sham stimulation