Physiological Constraints Associated With Trail Running (UT4M2018)

Grenoble Alpes University Hospital Center (CHU)

Status: Completed

Conditions: Muscle Fatigue

Treatments: Other: Pre and post running evaluations

Study type: Interventional

Funder types: Other

Identifiers

NCT03712592

38RC18.096

Details and patient eligibility

About

The practice of mountain running or "trail" is in full development in France and elsewhere in the world. This sporting practice associates specific physiological constraints related in particular to the duration of the efforts made (several hours) and to the ground (important elevation, technical ground, average altitude). Some studies have allowed the last 10 years to initiate the exploration of the physiological consequences of this type of practice, especially from a muscular point of view. However, some important questions remain to be clarified such as the impact of these sports events on fatigue and muscle recovery, cardiovascular, energy and water balance disturbances caused, induced sleep changes and the kinetics of recovery of the various parameters. . These elements remain in particular to be studied in very different racing contexts as currently developed by the organizers, namely race in one stage from long to very long distances (40 to 160 km) and race in stages (4 days, 4 x 40 km) as encountered in the Grenoble UT4M race (Ultra Tour des 4 Massifs).

Enrollment: 83 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Man or woman
• 18-55 years
• Absence of chronic cardiovascular, respiratory, metabolic or neuromuscular disease
• > 3 years of trail running (at least 1 race> 40 km / year completed and a race> 100 km completed (trail group 160 km)
• Medical certificate of no contraindication to the practice of the trail
• Subjects available in Grenoble before and within 15 days after the race
• Subjects affiliated to a social security scheme
• Subjects able to sign informed consent.

Exclusion criteria

• Cardiorespiratory, metabolic and neurological diseases
• Non-Echogenic Subjects
• Subjects with chronic sleep disorders
• Psychiatric pathologies or ATCD of behavioral disorders
• Persons refusing to sign the information sheet and the participation agreement,
• persons under guardianship or not subject to a social security scheme,
• Pregnant woman, parturient, breastfeeding mother
• Person deprived of liberty by judicial or administrative decision,
• Person subject to a legal protection measure, who can not be included in clinical trials.

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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83 participants in 4 patient groups

160km

Experimental group

Treatment:

Other: Pre and post running evaluations

40km

Experimental group

Treatment:

Other: Pre and post running evaluations

100km

Experimental group

Treatment:

Other: Pre and post running evaluations

4x40km

Experimental group

Treatment:

Other: Pre and post running evaluations