Physiological Response and Visual Attention to Visual Food Images in Healthy Subjects and in Functional Dyspepsia Patients

University Hospital Tuebingen

Status: Completed

Conditions: Functional Dyspepsia

Treatments: Behavioral: visual images

Study type: Interventional

Funder types: Other

Identifiers

NCT02727556

041/2016BO2

Details and patient eligibility

About

In functional dyspepsia (FD), abnormal cognitive and emotional changes such increased sensitization, anxiety, and depression scores have been reported in addition to the peripheral changes in gastrointestinal tract functions. In this study, investigators will evaluate the activity of autonomic nervous system, emotional response, and visual attention to food and non-food images in 30 male and female FD patients and 30 age/gender-matched healthy volunteers. These data will provide a new finding of the influence of impaired cognitive processing of food on symptom generation in functional gastrointestinal disorder patients.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male and female, volunteering adults BMI: 18-25 kg/m² right-handed Age: 18-65 years Capacity to give informed consent For FD patients, Diagnosis of functional dyspepsia over the last 12 months certified by a medical record Inconspicuous gastroscopy during the last 6 months certified by a medical record

Exclusion criteria

• Visual impairment Severe psychiatric illness (e.g. schizophrenia, severe depression (BDI-II:29-63)), substance dependence and abuse Intake of antidepressants / antipsychotics

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

Functional dyspepsia patient

Experimental group

Description:

Visual stimuli of food and non-food images will be presented to patients. Non-food images include positive, neutral, negative emotional pictures.

Treatment:

Behavioral: visual images

Healthy

Experimental group

Description:

Visual stimuli of food and non-food images will be presented to participants. Non-food images include positive, neutral, negative emotional pictures.

Treatment:

Behavioral: visual images