Physiological Response of Cortisol to Cardiac Catheterization

Creighton University

Status: Completed

Conditions: Adrenal Insufficiency

Study type: Observational

Funder types: Other

Identifiers

NCT01822847

12-16583

Details and patient eligibility

About

Cortisol is essential for survival. The importance of cortisol response is most apparent in patients with partial or complete deficiency of glucocorticoids during stressful events such as illness or surgery.

Full description

It is known that cortisol and other stress hormones increase during acute myocardial infarction as well (9-11). Cardiac catheterization is an essential tool for the management of acute coronary syndrome, and for the evaluation of the burden of coronary artery disease in cardiac patients.

Enrollment: 24 patients

Sex: All

Ages: 20 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing elective cardiac catheterization, who are willing and able to give consent.

Exclusion criteria

• • Patients with .primary or secondary adrenal insufficiency.

  • Patients taking steroids in the doses equivalent of at least 5 mg of prednisone daily for more than 3 weeks in the previous year.
  • Patients undergoing cardiac catheterization in the setting of acute coronary syndrome, eg. STEMI, NSTEMI and unstable angina.
  • Patients with low albumin level (<3.5 g/dL)

Trial design

24 participants in 1 patient group

catheterization

Description:

patients undergoing elective heart catheterization