Physiopathological Study of Autonomic Failure in Parkinson's Disease (SYNAPark)

Nantes University Hospital (NUH)

Status: Completed

Conditions: Parkinson's Disease

Treatments: Other: Autonomic dysfunction questionnaires; Other: Electrophysiological tests; Other: Biopsies of peripheral autonomic nervous system

Study type: Interventional

Funder types: Other

Identifiers

NCT01748409

RC12_0264

Details and patient eligibility

About

The aim of the study is to evaluate the autonomic failure in Parkinson's disease by clinical, electrophysiological and neuropathological examination.

Enrollment: 47 patients

Sex: All

Ages: 45 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with Parkinson's disease
• ages 45 to 80 years, both genders
• patients who signed informed consent

Exclusion criteria

• autonomic function modifying treatment
• pre-existing neuropathy or risk factors for neuropathy
• dementia
• colonic disorders
• coagulation disorders (may be due to treatment)

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)