Physiopathology and Sequelae of COVID-19 Infection (SEQ-COV-PHYSIO)

Centre Hospitalier Universitaire, Amiens

Status: Active, not recruiting

Conditions: TSH; Covid19; Cortisol

Treatments: Biological: blood test

Study type: Interventional

Funder types: Other

Identifiers

NCT04563676

PI2020_843_0096

Details and patient eligibility

About

The data obtained from Covid-19 infections seem to suggest that the immunogenesis of Covid-19 could in some cases be the result of immune dysregulation. On the other hand, endocrine damage is possible at the tile of Covid-19 infection (mainly thyroid,adrenal, and hypothalamus). These disorders are autoimmune or linked to degeneration.

The main objective is to assess the thyroid function (thyrotropic axis) as well as the corticotropic adrenal function of patients who have had Copvid-19 pneumonia. The secondary objectives is to describe the pathophysiological mechanisms of pulmonary and vasculothrombotic involvement of Covid-19

Enrollment: 400 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient having a covid19 infection hospitalized at the Amiens Picardie University Hospital
• Patient who is seen in Pneumology consultation for a respiratory assessment at 3 months of his hospitalization (between M2 and M4) to evaluate presence of respiratory sequelae
• Patient who agreed to participate in the protocol
• Patient affiliated to a Social Security

Exclusion criteria

• patient under guardianship or curators
• patient refusing to participate

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)