Physiotherapy and Reaction Time in Hemophilia

Yuzuncu Yıl University

Status: Completed

Conditions: Hemophilia Arthropathy

Treatments: Other: Home exercise; Other: Manual therapy; Other: Supervised exercise; Device: Neuromuscular electrical stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT06331091

YuzuncuYıl2022/2

Details and patient eligibility

About

This randomised controlled study was conducted to investigate the comprehensive physiotherapy combined with home exercises on individuals with hemophilic arthropathy in the lower extremity. There are two groups in the study: home exercises and comprehensive physiotherapy combined with home exercises. Is physiotherapy combined with home exercises superior to home exercises on joint health, bleeding frequency, reaction time, dynamic balance, muscle strength? The aim of this study is to increase the compliance of hemophilic individuals to physiotherapy and adapt home exercises to their lives with weekly sessions.

Full description

Introduction: The positive effects of physiotherapy and exercise on joint health, frequency of hemartrosis (FoH) in patient with hemophilic arhropathy (PwHA) are well explained in the literature. However, adaptation problems to physiotherapy sessions (usually 3 times a week) may cause PwHA to ignore the need for therapy. It may be more beneficial for PwHA to adapt physiotherapy and exercise into daily live.

Aim: To investigate the effect of a once-a-week physiotherapy combined with home exercises on joint health, FoH, muscle strength, pain, reaction time and dynamic balance.

Methods: 20 patients have hemophilic arthropathy in knee and/or ankle were randomly divided into 2 groups, named home exercise (HE) and comprehensive physiotherapy combined with home exercise (CPcwHE). In the clinical assessment, HJHS, manuel muscle tester, Fitlight® system for reaction time, functional reach test for dynamic balance were used and questioned the number of bleedings in the last 6 weeks for FoH. The CP group received comprehensive physiotherapy (manual therapy, neuromuscular electrical stimulation and exercises) 1 day a week, and did the exercises at home the other 2 days a week. The HE group performed the exercises given to CP at home 3 times a week. Evaluations were repeated at the end of 6 weeks.

Enrollment: 21 patients

Sex: Male

Ages: 10 to 32 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: -Clinical diagnosis of hemophilia

-Clinical diagnosis of hemophilic arthropathy in ankle and/or

Exclusion Criteria:

• Clinical diagnosis of any neurological disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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21 participants in 2 patient groups

Home exercise

Active Comparator group

Description:

This group performed the same exercises given to comprehensive physiotherapy group at home 3 times a week for 6 weeks.

Treatment:

Other: Home exercise

Comprehensive physiotherapy

Experimental group

Description:

This group received comprehensive physiotherapy (manual therapy, neuromuscular electrical stimulation and exercises) 1 day a week, and did the exercises at home the other 2 days a week for 6 weeks.

Treatment:

Other: Supervised exercise

Other: Manual therapy

Device: Neuromuscular electrical stimulation

Other: Home exercise