PiCCO Guided Therapy in Liver Cirrhosis

Heidelberg University

Status: Completed

Conditions: Liver Cirrhosis

Treatments: Procedure: Hemodynamic monitoring system PiCCO

Study type: Interventional

Funder types: Other

Identifiers

NCT00232427

PiCCO

Details and patient eligibility

About

Prospective comparison of standard therapy in liver cirrhosis versus standard therapy plus intensified hemodynamic monitoring using the PiCCO system.

Full description

Patients presenting with advanced liver cirrhosis will receive either standard treatment or standard treatment plus hemodynamic monitoring with the PiCCO device. Fluids and vasoacitve drugs will be administered according to the measurements over a period of 5 days.

Enrollment: 20 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Liver cirrhosis Child-Pugh-Score > 7
• Ascites > 500 ml

Exclusion criteria

• Coronary heart disease
• Apoplexia < 6 months ago
• Vasculitis
• Thrombosis
• Arterial occlusive disease > stadium II

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)