Piezoelectric Vibrations and Tissue, Cellular and Molecular Mechanisms of Oral Wound Healing After Third Molar Surgery

University of Belgrade

Status: Completed

Conditions: Tooth, Impacted

Treatments: Procedure: piezo surgery; Procedure: conventional surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT02942108

36/20

Details and patient eligibility

About

The aim of this clinical trial is to investigate and compare the effect of piezoelectric surgery on tissue, cellular and molecular level of oral surgical wound healing and postoperative outcomes (pain, swelling, trismus) after lower third molar surgery in healthy patients

Enrollment: 40 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• bilaterally symmetrically impacted lower third molars

Exclusion criteria

• presence of intraoral infection
• chronic orofacial pain
• pregnancy/ lactation
• heavy tobacco smokers
• alcohol/ drug abuse
• allergic reaction to medicaments used

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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40 participants in 2 patient groups

healthy, conventional surgery

Active Comparator group

Description:

Surgical bone removal by conventional rotary burs in healthy patients during third molar surgery

Treatment:

Procedure: conventional surgery

healthy, piezo surgery

Experimental group

Description:

Surgical bone removal by piezoelectric vibrations in healthy patients during third molar surgery

Treatment:

Procedure: piezo surgery