Pilot 99mTechnetium-MIBI Single Photon Emission Computed Tomography - Computed Tomography (SPECT-CT) in Papillary Carcinoma (CA) Thyroid

Chulalongkorn University

Status: Unknown

Conditions: Papillary Thyroid Cancer

Treatments: Radiation: 99mTc-MIBI SPECT-CT

Study type: Interventional

Funder types: Other

Identifiers

NCT00984191

NapadonChula_01

Details and patient eligibility

About

The purpose of this trial is to see if the 99mTechnetium-MIBI SPECT-CT can be a tool for preoperative evaluation of cervical node metastasis in papillary thyroid cancer.

Enrollment: 15 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• papillary thyroid cancer

Exclusion criteria

• pregnancy
• Bleeding abnormality
• Prior history of head and neck cancer
• can not perform 99mTechnetium-MIBI SPECT-CT
• can not perform 131I remnant Ablation
• Prior any head and neck surgery within 3 months
• Prior deep neck infection within 3 months

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

15 participants in 3 patient groups

99mTc positive

Experimental group

Description:

99mTechnetium-MIBI SPECT-CT positive compare : Scan - Pathologic report

Treatment:

Radiation: 99mTc-MIBI SPECT-CT

99mTc Negative_Neck dissection

Experimental group

Description:

99mTc Negative but have neck dissection indication compare : 99mTc - Pathologic report

Treatment:

Radiation: 99mTc-MIBI SPECT-CT

99mTc Negative_No neck dissection

Experimental group

Description:

99mTc Negative and No other indication for neck dissection compare : 99mTc - 7. 131I (post-treatment) whole body scan

Treatment:

Radiation: 99mTc-MIBI SPECT-CT