Pilot Investigation of Dual Energy CT Imaging on an Online Adaptive Radiation Therapy System

University of Michigan Rogel Cancer Center

Status: Enrolling

Conditions: Malignant Pelvic Neoplasm; Genitourinary System Carcinoma

Treatments: Other: Non-Interventional Study

Study type: Observational

Funder types: Other

Identifiers

NCT07219134

NCI-2025-03767 (Registry Identifier)

HUM00259510 (Other Identifier)

UMCC 2024.027

Details and patient eligibility

About

This study is being done to see if researchers can find a better way to image a patient's tumor during radiation treatment.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• * Patients with pelvis or genitourinary (GU) cancer requiring standard of care radiotherapy treatment

  • All adults, defined as individuals of 18 years of age or greater
  • Radiotherapy treatment will be performed on the Varian Ethos radiotherapy system
  • Ability to understand and the willingness to sign a written informed consent

Exclusion criteria

• * Minors, defined as individuals less than 18 years of age

  • Pregnant or nursing female

Trial design

30 participants in 1 patient group

Observational

Description:

Patients undergo lower beam energy CBCT scan once during standard of care radiation therapy on study.

Treatment:

Other: Non-Interventional Study