Pilot Study Assessing the Feasibility and Impact of a Remote Adapted Physical Activity Program on Quality of Life in Patients With Inflammatory Bowel Disease (IBD) (APIMICI)

Raincy Montfermeil Hospital Group

Status: Enrolling

Conditions: Inflammatory Bowel Disease (Crohn&Amp;#39;s Disease and Ulcerative Colitis); Inflammatory Bowel Disease (IBD)

Treatments: Procedure: adapted physical activity

Study type: Interventional

Funder types: NETWORK; Industry

Identifiers

NCT07191106

GHIRM_RIRCM20241122

Details and patient eligibility

About

Inflammatory Bowel Disease (IBD) is a chronic relapsing condition that affects the gastrointestinal tract and is increasingly diagnosed in adolescents and young adults. Although anti-TNFα therapies are effective in reducing disease activity and improving quality of life, they are frequently associated with side effects such as fatigue, weight gain, and joint pain, which may be mitigated by regular physical activity.

Emerging evidence suggests that light to moderate physical activity may help reduce systemic and intestinal inflammation and improve IBD-related outcomes. However, access to structured physical activity programs remains limited, and personal or professional constraints may hinder participation.

This pilot study aims to assess the feasibility and impact of a remotely delivered Adapted Physical Activity (APA) program on the quality of life of patients with Inflammatory Bowel Disease (IBD), including Crohn's disease and ulcerative colitis. This study evaluates the effects of a 12-weeks remote APA intervention on quality of life as the primary outcome.

Secondary objectives include assessing changes in anxiety and depression, fatigue levels, IBD activity, and smoking behavior. The findings from this study may inform the development of scalable, non-pharmacological strategies to support symptom management and well-being in individuals with IBD.

Enrollment: 72 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 18 years and older
• Diagnosis of Inflammatory Bowel Disease (IBD) established for at least 6 months
• Patient is motivated to participate in the Adapted Physical Activity (APA) program
• Medical certificate confirming fitness to engage in remote physical activity
• Access to a digital device with internet connectivity enabling use of the MOOV+ application at home
• Written informed consent freely given after appropriate information
• Affiliation with, or beneficiary of, a national health insurance system

Exclusion criteria

• Patients under 18 years of age

• Medical contraindication to physical activity

• High levels of physical activity as defined by the International Physical Activity Questionnaire (IPAQ):

  • Total >1500 MET-min/week of vigorous activity on at least 3 days, OR
  • Total physical activity >3000 MET-min/week, regardless of distribution

• Presence of psychological disorders that may interfere with study participation

• Lack of access to a device or internet connection enabling remote participation

• Pregnant or breastfeeding women

• Patients under legal guardianship or curatorship

• Patients under legal protection

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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72 participants in 1 patient group

Pre- and post-intervention comparison following participation in the Adapted Physical Activity (APA)

Experimental group

Description:

There is no comparator group at this stage of the research. Patient data will be compared before and after participation in the Adapted Physical Activity (APA) program.

Treatment:

Procedure: adapted physical activity