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Pilot Study for Noninvasive Spectroscopic Detection of Adipose Tissue Inflammation in Obesity

Rockefeller University logo

Rockefeller University

Status

Completed

Conditions

Obesity

Treatments

Procedure: Fat Biopsy

Study type

Observational

Funder types

Other

Identifiers

NCT01900366
JAL-0809

Details and patient eligibility

About

This study will test the potential of two techniques using light properties of adipose tissue to diagnose crown-like structures and inflammation to be compared with pathologic examination of adipose tissue biopsies from ongoing clinical studies.

Full description

Adipose tissue (fat) inflammation is emerging as an important harbinger of disease development including Type 2 diabetes, heart disease and potentially cancer. The hallmark feature of adipose tissue inflammation is the crown-like structure, a dying fat cell surrounded by immune cells attempting to clear the damage. Current methods for detecting adipose tissue inflammation rely on invasive procedures such as fat biopsies. We propose developing methods that use the light reflection properties of inflamed adipose tissue as a potential non-invasive method to detect adipose tissue inflammation.

Enrollment

14 patients

Sex

All

Ages

18 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

-Subjects currently enrolled in a current Rockefeller University study who will be undergoing adipose tissue biopsies as part of the study protocol

Exclusion criteria

-History of any skin disease

Trial design

14 participants in 2 patient groups

Obese subjects for fat biopsy
Description:
10 patients recruited during fat biopsies for sample collection
Treatment:
Procedure: Fat Biopsy
Lean controls for fat biopsy
Description:
5 Lean controls will be recruited
Treatment:
Procedure: Fat Biopsy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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