Evaluation of a Dietary Supplement Containing Melissa Officinalis Formulated in Phospholipids on Mood Well-being and Cortisol Modulation

Azienda di Servizi alla Persona di Pavia

Status

Begins enrollment in 4 months

Conditions

Emotional Well-being

Mood Disorders

Stress

Treatments

Dietary Supplement: Melissa officinalis supplement

Study type

Interventional

Funder types

Other

Identifiers

NCT06942897

1267/21092023

Details and patient eligibility

About

This is a randomized, double-blind, placebo-controlled pilot study designed to evaluate the effect of an oral nutritional supplement containing Melissa officinalis formulated in phospholipids on mood and cortisol levels in healthy adults. Participants will be randomly assigned to receive either the active supplement or a placebo daily for 3 weeks. The primary outcome measures include changes in mood well-being, perceived stress, and salivary cortisol levels. The study aims to assess both efficacy and safety of the supplement in modulating stress response and emotional balance.

Enrollment

40 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age between 18 and 65 years
Healthy volunteers as assessed by medical history and physical examination
Willingness to comply with the study procedures

Exclusion criteria

Current use of medications or supplements that may affect mood or cortisol levels
Known allergy or sensitivity to Melissa officinalis or phospholipids
History of psychiatric disorders (e.g., major depression, anxiety disorders)
Significant comorbidities (e.g., cardiovascular, hepatic, renal diseases)
Pregnant or breastfeeding women
Participation in another clinical trial in the past 30 days