Pilot Study Freeze and Transport Immune Cells

National Institute of Allergy and Infectious Diseases (NIAID)

Status: Completed

Conditions: Poliomyelitis; Diphtheria; Tetanus; Pertussis; Hepatitis B

Study type: Observational

Funder types: NIH

Identifiers

NCT00138268

03-236

Details and patient eligibility

About

To evaluate and standardize umbilical cord specimen collection and laboratory procedures to evaluate cellular and serological immune responses in neonates and young infants

Full description

To evaluate: 1) The procedures for obtaining umbilical cord blood; 2) the methods for ensuring immune cell viability, freezing, and shipping; 3) the conditions for optimization of immune cell isolation procedures.

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

For the portion of the pilot study conducted at the UCLA CVR, an umbilical cord blood sample will be obtained from approximately 8 to 12 healthy pregnant women who are delivering neonates at the Obstetrical delivery ward of Harbor- UCLA Medical Center. Informed consent will not be obtained because the blood will be obtained after delivery from a clamped umbilical cord attached to the placenta (afterbirth) that otherwise would be discarded.

Exclusion criteria

A cord blood sample will not be collected from women who have requested special arrangements for a cord blood registry service.