Pilot Study of Auto-immune Abnormalities Associated With Down Syndrome (IMMUTRI)

Institut Jerome Lejeune

Status: Completed

Conditions: Down Syndrome With and Without Auto Immune Abnormalities

Study type: Observational

Funder types: Other

Identifiers

NCT01041469

IJL-IMM-EP10

Details and patient eligibility

About

The purpose of the study is to identify biological data linked to auto immune abnormalities associated with Down Syndrome.

Enrollment: 72 patients

Sex: All

Ages: 8 to 36 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Free and complete trisomy 21
• aged between 8 and 36 years
• biological or clinical signs of auto-immune disorder (group 1)
• no sign of auto-immune disorder (group 2)

Exclusion criteria

• any antimitotic or immune depressing treatment during the last 6 months
• Current infectious disease
• Corticosteroid therapy in the last 3 weeks
• pregnancy

Trial design

72 participants in 2 patient groups

with abnormalities

Description:

Down syndrome patients presenting with at least one sign of auto immune abnormality

without abnormality

Description:

Down syndrome patients without any sign of recognized auto immune condition