Pilot Study of Effects of Cold Vests on Cardiovascular Risk Markers

University Hospital, Linkoeping

Status: Completed

Conditions: Cardiovascular Risk Factors; Basal Metabolic Rate

Treatments: Other: cold vest

Study type: Interventional

Funder types: Other

Identifiers

NCT02340598

2014/432-31

Details and patient eligibility

About

Randomized trial of supplying a cold vest as compared with controls (no cold vest) on cardiovascular risk factors such as blood lipids, insulin, blood pressure and body weight and also on basal metabolic rate. Recruitment of 100 participants and 70 are randomized to being given a vest which they can use to increase basal metabolic rate during 1-2 hours (as long as the pre-cooled vest stays cool) by activating brown adipose tissue and/or shivering. The remaining 30 subjects will constitute a control group. Lab tests and anthropometrics are checked at baseline, after 2 months and after 1 year.

Enrollment: 50 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy subjects that have no known metabolic relevant diseases

Exclusion criteria

• thyroid disease,
• mental disorders,
• language problems

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

cold vest

Experimental group

Description:

Participants are given a cold vest that the pre-cool in a freezer. They are encouraged to use it daily to activate metabolism through brown adipose tissue and shivering.

Treatment:

Other: cold vest

control

No Intervention group

Description:

No intervention, just recording of risk factors and basal metabolic rate.