Pilot Study of Familial Nonsyndromal Mondini Dysplasia

National Center for Research Resources (NCRR)

Status: Completed

Conditions: Mondini Dysplasia

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00004336

UMMC-1402

199/11895

Details and patient eligibility

About

OBJECTIVES:

I. Determine the mode of inheritance of nonsyndromal Mondini inner ear dysplasia, an inner ear malformation causing deafness, vestibular dysfunction, and recurrent meningitis.

Full description

PROTOCOL OUTLINE:

The parents of 1 family with known Mondini dysplasia are screened for the disorder using temporal bone computerized tomography without contrast. This information is used to determine the mode of inheritance.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

PROTOCOL ENTRY CRITERIA:

Parents of a study family with nonsyndromal Mondini dysplasia