Pilot Study of the Effects of Erythritol on Endothelial Function in Patients With Type 2 Diabetes Mellitus

Boston University

Status: Completed

Conditions: Type 2 Diabetes Mellitus

Treatments: Dietary Supplement: Erythritol-containing beverage

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01609088

H-31447

Details and patient eligibility

About

The study will determine whether acute and chronic consumption of a beverage containing erythritol will improve endothelial function in patients with type 2 diabetes mellitus.

Enrollment: 24 patients

Sex: All

Ages: 35 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type 2 diabetes mellitus
• Otherwise healthy

Exclusion criteria

• Pregnant
• BMI>35 kg/m2
• Long acting insulin treatment
• Other major illness, drug abuse
• Treatment with an investigational drug within 12 weeks
• Treatment with dietary or vitamin supplements
• Smoking within 3 months

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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24 participants in 1 patient group

Erythritol-containing beverage

Experimental group

Treatment:

Dietary Supplement: Erythritol-containing beverage