Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy

University of California Irvine (UCI)

Status: Enrolling

Conditions: Skin Lesion

Treatments: Device: MPTflex-multiphoton microscopy-based tomograph.

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT01771718

20118494

R01EB026705 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features. .

Full description

This study is performed using a multiphoton microscopy-based tomograph (MPTflex) developed by JenLab, GmbH (Germany) to image non-invasively normal and lesional skin. Skin lesions are imaged by multiphoton microscopy and images are compared to those obtained from histopathology through standard of care processed skin biopsies.

Any biopsies will be performed by the health care provider as a standard of care procedure.

Enrollment: 250 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or Female all age groups
• Ability to understand and carry out subject instructions

Exclusion criteria

• Pregnant women

Trial design

250 participants in 1 patient group

Human skin

Description:

Multiphoton microscopy imaging to collect information about changes in skin cells and fibrilar structure.

Treatment:

Device: MPTflex-multiphoton microscopy-based tomograph.