Pilot Study to Characterize the Microbiome in Cutaneous T Cell Lymphoma Skin Lesions Before and After Use of CLn® Skin Care Body Wash

Northwestern University

Status: Not yet enrolling

Conditions: Cutaneous T Cell Lymphoma

Treatments: Other: CLn Body Wash

Study type: Observational

Funder types: Other

Identifiers

NCT06665490

STU00222221

Details and patient eligibility

About

In this pilot study of patients with mycosis fungoides, the most common form of CTCL, we propose to primarily evaluate the impact of daily use of the CLn Body Wash (dilute sodium hypochlorite (0.006% NaOCl)) on the microbiota of CTCL lesions. Should dilute sodium hypochlorite body wash improve the microbiome of MF, reducing the abundance of S. aureus, future, larger studies can more fully evaluate the impact on pruritus, erythema, scaling, disease evolution and its role in CTCL management.

Enrollment: 15 estimated patients

Sex: All

Ages: 18 to 89 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults ages 18-89 years of age with active mycosis fungoides.
• Patients with concurrent and prior malignancies are allowed as long as any concurrent malignancy does not directly involve the same skin site.

Exclusion criteria

• Patients currently or recently (within past 4 weeks) on topical or systemic antibiotics, pregnant persons, or persons with potential of becoming pregnant or are/will be breastfeeding
• Patients that have initiated a new skin-directed therapy over the past month.

Trial design

15 participants in 1 patient group

Mycosis Fungoides patients

Description:

Patients with mycosis fungoides will be enrolled at Northwestern Memorial Hospital Dermatology

Treatment:

Other: CLn Body Wash