Pilot Study to Measure Uric Acid in Traumatized Patients: Determinants and Prognostic Association

Montreal Sacred Heart Hospital

Status: Unknown

Conditions: Inflammation; Trauma

Study type: Observational

Funder types: Other

Identifiers

NCT03622632

263425

Details and patient eligibility

About

The goal of this project, is to better understand the fluctuation of the level of uric acid in traumatized patients by making serial measurements during their hospitalization in the intensive care unit. In addition, the determinants (e.g. type of trauma, diseases, interventions) of the blood level of uric acid and its association with the development of organ failure will be sought.

Enrollment: 25 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Direct admission to trauma center
• ≤ 3h after trauma
• ISS ≥ 16
• Received at least 1L of fluid at ER entrance

Exclusion criteria

• Isolated head injury
• Isolated spine injury
• Chemotherapy within the last month
• Hematologic disease
• Chronic hemodialysis
• Uricase treatment within the last week
• Expected death within 48h