Pilot Study Using Echocardiography to Evaluate Patients With Heart Failure and Dyssynchrony Who Have a CRT-D Device

University of Mississippi

Status: Withdrawn

Conditions: Systolic Heart Failure

Study type: Observational

Funder types: Other

Identifiers

NCT01127334

2010-0069

Details and patient eligibility

About

Out of all the patients that receive a CRT-D ( a dual chamber pacemaker with defibrillator ) for cardiac resynchronization therapy there is approximately one-third that do not respond. We believe that by using a simple technique that includes routine echocardiography that are normally performed in these patients could help us better understand how to program their device to reach better optimization.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Adults age 18-110 years
2. Must have a CRT-D (A biventricular pacemaker with defibrillator)
3. Last optimization of their device (CRT-D) must not have been done in the past 3 months
4. Must be optimal heart failure medical regimen. This includes target dose of beta-blocker and angiotensin converting enzyme inhibitor (ACE-I) (or equivalent; i.e angiotensin receptor blocker (ARB); or balanced preload and afterload reducers with hydralazine and nitrates.)

Exclusion criteria

1. Less than 18 years of age or greater than 110 years old.
2. Does not have a CRT-D
3. Optimization of their device has occurred in the past 3 months
4. Not on optimal medical therapy for heart failure as listed in the inclusion criteria.

Trial design

0 participants in 1 patient group

Systolic Heart Failure, Dyssynchrony, CRT-D

Description:

Patients with systolic heart failure and dyssynchrony that have a CRT-D that have not been optimized in the past 3 months.