Pilot-testing the Effect of Magnetic Mitohormesis Therapy for Treating Frailty in Older Adults

Auburn University

Status: Enrolling

Conditions: Frailty

Treatments: Other: Magnetic Mitohormesis Therapy

Study type: Interventional

Funder types: Other; NETWORK

Identifiers

NCT05930470

AU MMT 23

Details and patient eligibility

About

Thirty (30) adults with limited physical function will be recruited to participate in a double-blind pilot randomized controlled crossover trial in which all participants will receive 12-weeks of twice weekly MMT treatment in the first (Phase 1) or second half (Phase 2) of the study period; during the control period, participants will receive sham treatment and will be blinded to the randomization.

Enrollment: 30 estimated patients

Sex: All

Ages: 60+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• physical frailty or pre-frailty, indicated by Short Physical Performance Battery Score <10;
• intact cognition indicated by a Mini-Cog Screening Test Score > 2;
• able to read and write in English; and
• access to a telephone.

Exclusion criteria

• active malignancy;
• neuro-degenerative disease
• active electronic implants;
• any health conditions that would prevent performing the testing and intervention procedures;
• major surgical procedures within the last 6 months;
• major change in prescription medications within the last 3 months

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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30 participants in 2 patient groups

Delayed intervention

Sham Comparator group

Description:

Sham treatment first, then Magnetic Mitohormesis Therapy treatment

Treatment:

Other: Magnetic Mitohormesis Therapy

Immediate intervention

Experimental group

Description:

Magnetic Mitohormesis Therapy treatment first, then Sham treatment

Treatment:

Other: Magnetic Mitohormesis Therapy