Adaptive Cell Phone Support (ACPS)

Children's Hospital Los Angeles

Status: Begins enrollment in a year or more

Conditions: Medication Adherence

Treatments: Behavioral: Adaptive Cell Phone Support; Behavioral: Computer-Delivered Cell Phone Support; Behavioral: Automated Text Reminders

Study type: Interventional

Funder types: Other

Identifiers

NCT07064824

CHLA-23-00149_Phase III

Details and patient eligibility

About

The goal of this pilot clinical trial is to test a mobile health intervention for promoting medication adherence in a population of adolescents and young adults with chronic health conditions. The main question it aims to answer is:

-Is an adaptive intervention (personalizing the intensity of support based on patients' needs) efficacious for promoting medication adherence Researchers will compare the adaptive intervention to automated text message reminders see if the adaptive intervention shows stronger positive effects on medication adherence.

Full description

Plan to enroll 96 participants in this study, which is a sequential randomized trial.

Enrollment: 96 estimated patients

Sex: All

Ages: 15 to 20 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Children's Hospital Los Angeles patient
• between 15-20 years old
• taking at least one oral medication per day for a chronic health condition
• English speaking
• demonstrating sufficient cognitive capacity to engage in the assent/consent process and study procedures

There is no exclusion criteria.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Sequential Assignment

Masking: None (Open label)

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96 participants in 3 patient groups

Adaptive Cell Phone Support

Experimental group

Description:

Computer-delivered cell phone support (reminders, problem-solving, referrals to resources) and responsive human coaching (phone calls, test messages, in-app messaging) to improve medication adherence.

Treatment:

Behavioral: Computer-Delivered Cell Phone Support

Behavioral: Adaptive Cell Phone Support

Computer-Delivered Cell Phone Support

Experimental group

Description:

Computer-delivered cell phone support (reminders, problem-solving, referrals to resources)

Treatment:

Behavioral: Computer-Delivered Cell Phone Support

Automated Text Reminders

Active Comparator group

Description:

Scheduled one-way text automated message reminders to take medication

Treatment:

Behavioral: Automated Text Reminders