Pilot Trial of Cognitive and Behavioral Treatment of Compulsive Hoarding Compared to Wait List Control

Boston University Charles River Campus

Status and phase: Completed; Phase 1

Conditions: Obsessive-Compulsive Disorder

Treatments: Behavioral: Cognitive Behavioral Treatment

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00073346

DATR A2-AIA

R21MH068539 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study developed and tested a specialized cognitive and behavioral treatment for the symptoms of hoarding disorder, including excessive acquiring, difficulty discarding items, and extensive clutter in the home.

Full description

Compulsive hoarding is characterized by excessive acquisition of possessions, difficulty discarding possessions, and excessive clutter. This condition is resistant to standard pharmacological and psychotherapeutic interventions that have proven effective in treating other obsessive compulsive spectrum disorders. This study aimed to determine the effectiveness of a specialized cognitive behavioral therapy (CBT) designed for treating hoarding symptoms.

This study consists of three phases. In Phase 1, pilot data from previous studies were examined to develop an intervention suitable for use in a waitlist trial. In Phase 2, pilot study information were used to develop and test a treatment manual for compulsive hoarding. During this phase, treatment was applied flexibly to allow for variations in treatment duration and choice of techniques. During Phase 3, participants were randomly assigned to 26 weekly sessions of CBT or to a 12-week wait-list control, followed by active treatment for a fixed duration of 26 sessions. Therapist adherence and competence were assessed through audiotaped therapy sessions.

Enrollment: 52 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Display at least moderately severe hoarding symptoms
• Must live within 45 minutes of Boston, MA or Hartford, CT

Exclusion criteria

• Ten or more sessions of cognitive behavior therapy for hoarding
• Concurrent psychotherapy or medications
• Suicidal, psychotic, or other psychiatric symptoms requiring hospitalization
• Compulsive buying symptoms that are part of a manic phase of bipolar disorder
• Mental retardation, dementia, brain damage, or other cognitive dysfunction that would interfere with the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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52 participants in 2 patient groups

cognitive behavior therapy for hoarding disorder

Experimental group

Description:

Cognitive behavior therapy included 26 sessions of motivational enhancements; skills training for sorting, organizing and problem solving; direct practice not acquiring new items and discarding possessions to remove clutter and organize possessions; cognitive therapy to evaluate beliefs about possessions; and relapse prevention skills.

Treatment:

Behavioral: Cognitive Behavioral Treatment

Wait list control

No Intervention group

Description:

Participants waited to receive treatment for 12 weeks