Place of Birth and Neonatal Health in Cases of Premature Birth Between 32 and 36 Weeks of Amenorrhoea (PREM3236)

University Hospital Center (CHU) Dijon Bourgogne

Status: Completed

Conditions: Premature Between 32 and 36 Weeks of Amenorrhoea

Study type: Observational

Funder types: Other

Identifiers

NCT06078618

DESPLANCHES APJ 2021

Details and patient eligibility

About

Moderate and late premature babies (32-36 weeks of amenorrhoea) account for around 6% of births, but 20% of neonatal deaths. These children also have an increased risk of neonatal morbidity and long-term neurodevelopmental sequelae compared with full-term newborns.

In the case of preterm birth, optimal antenatal, birth and postnatal management is necessary to prevent neonatal complications and mitigate longer-term consequences. However, we lack knowledge about the management of this at-risk population and the factors influencing their health.

This knowledge is needed in the current context of unfavourable trends in neonatal health. Over the last ten years, neonatal and infant mortality has stagnated in France, with France falling behind other European countries. According to the latest European report, France ranks 22nd out of 33 countries. The causes of this stagnation are not well known, but many hypotheses have been put forward, including sub-optimal organisation of care.

Enrollment: 240,000 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• All mothers and their newborn babies (live or stillborn) who had a delivery stay between 32 and 36 days of age recorded in the PMSI between 01/01/2015 and 31/12/2020.

Exclusion criteria

• Births in very small maternity units
• Births in hospitals without an obstetrics unit
• Births outside hospitals.

Trial design

240,000 participants in 1 patient group

cohort

Description:

Mothers and their newborn babies (live or stillborn) who were delivered between 32 and 36 weeks' gestation