PLAN-A Data- Bio- and Plan- Bank Collection for SCCA in Denmark

Aarhus University Hospital

Status: Active, not recruiting

Conditions: Anal Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT05570279

KFE-1523

Details and patient eligibility

About

The study is a prospective registration of treatment related-, toxicity-, Quality of life- and outcome data from patients treated in Denmark with radiotherapy for squamous cell carcinoma of the anus (SCCA), as a cooperation within the Danish Anal Cancer Group (DACG).

Substudy one: A prospective biobank is collected with the purpose to identify predictive and prognostic markers for outcome.

Substudy two: MRI scans are performed to investigate the rate of pelvic insufficience fractures at one year post chemoradiotherapy.

Enrollment: 314 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18
• Squamous cell carcinoma of the anus, and indication for curatively intended radiotherapy
• Written and oral consent

Exclusion criteria

• Contraindication to blood sampling or MRI scans (substudy 1 and 2)
• Other malignant disease within 5 years except from basal cell carcinomas