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Planned Vaginal Delivery vs Planned Cesarean Delivery in Preterm Twins

University Hospital Center (CHU) logo

University Hospital Center (CHU)

Status

Completed

Conditions

Twin Pregnancy

Treatments

Other: Survival without severe morbidity
Other: Survival at discharge

Study type

Observational

Funder types

Other

Identifiers

NCT04232436
RECHMPL20_0035

Details and patient eligibility

About

The incidence of twin pregnancies has increased and currently accounts for 1.8% of all deliveries. 47.5% of twins are born prematurely (vs. 6% for singletons) of which 9.9% before 32SA. Caesarean section rates are also higher than for singletons (53.7% vs 19.2%) and 31.8% of caesarean sections are performed before delivery.

The optimal mode of delivery for preterm twins remains controversial. The latest recommendations for clinical practice emphasize that it is not appropriate to recommend one mode of delivery rather than another in the case of twin pregnancies at any term.

In view of all these elements, we wished to carry out a retrospective study at the Montpellier University Hospital in order to compare the neonatal outcome of preterms twins according to their mode of delivery : planned vaginal delivery versus planned cesarean delivery.

Enrollment

204 patients

Sex

Female

Volunteers

No Healthy Volunteers

Inclusion criteria

  • twins born at Montpellier University Hospital
  • between 24SA and 32SA+6
  • January 2010 to July 2019
  • The mothers must have gone into labour spontaneously or after preterm rupture of membranes
  • first twin in cephalic presentation

Exclusion criteria

  • twin to twin transfusion syndrome
  • monoamniotic pregnancies
  • cause of delivery other than preterm labor or preterm rupture of membranes
  • lethal malformation
  • first twin in breech or transverse presentation

Trial design

204 participants in 2 patient groups

Planned vaginal delivery
Description:
Planned vaginal delivery
Treatment:
Other: Survival without severe morbidity
Other: Survival at discharge
Planned cesarean delivery
Description:
Planned cesarean delivery
Treatment:
Other: Survival without severe morbidity
Other: Survival at discharge

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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