Planning Margin Requirements for Pediatric Radiation Oncology

St. Jude Children's Research Hospital

Status: Completed

Conditions: Pediatric Radiation

Study type: Observational

Funder types: Other

Identifiers

NCT00704613

RTMRG1

Details and patient eligibility

About

The planning target volume (PTV) and planning organ at risk volume (PRV) margins used for pediatric radiation therapy are empiric, and quantitative assessment of these margins is needed to improve therapy planning and delivery.

Full description

Data will be gathered to develop a model to quantify the setup margin (SM) portion of the planning target volume (PTV) margin for pediatric tumor sites according to age, localization technique, treatment position, and the use of general anesthesia. Patient specific PTV and PRV margin recommendations will be developed based on the number of participants.

Enrollment: 375 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients will receive conformal or intensity-modulated radiation therapy (3D or IMRT).
• Research participant or legal guardian/representative gives written informed consent.

Exclusion criteria

• Unwillingness of research participant or legal guardian/representative to give written informed consent