Plant-Based Meat vs Animal "Red" Meat Trial (FOOD-1)

McGill University

Status: Completed

Conditions: Inflammatory Response

Treatments: Other: Plant-based patties group; Other: Red meat patties group

Study type: Interventional

Funder types: Other

Identifiers

NCT04510324

2020-6374

Details and patient eligibility

About

To assess the changes in the circulating levels of TMAO after 1-week of beef or plant-based burger diet.

Full description

Single-center, randomized, single-blinded cross-over trial including healthy adult participants (N=40, omnivores, aged between 25 and 65 years, and with a body mass index (BMI) between 20 and 40 kg/m2 (see participation criteria below). Participants will be randomized to either red meat (cow burger) or plant "meat" (plant-based burger). The primary outcome will be the within-group change in the TMAO levels.

Enrollment: 41 patients

Sex: All

Ages: 25 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ≥ 25 years and ≤65 of age
• BMI ≥20 Kg/m2 and ≤40 Kg/m2
• No known kidney disease
• No antibiotics in the previous 30 days

Exclusion criteria

• Any person who does not meet the above criteria and/or who refuses to participate
• Food allergies (specific ingredients contained in the patties)

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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41 participants in 2 patient groups

Red meat patties

Active Comparator group

Description:

Participants will be randomized to group 1: Red meat, ''Costco Kirkland Signature 1/4 lb Ground Beef Patties'' (Beef burger). Participants will be given two patties per day.

Treatment:

Other: Red meat patties group

Plant-based patties

Experimental group

Description:

Participants will be randomized to group 2: plant-based burger which contains no animal products. The Plant-based burger selected is ''Beyond Burger" (https://www.beyondmeat.com/products/the-beyond-burger/ ). Participants will be given two patties per day.

Treatment:

Other: Plant-based patties group