Plaque Registration and Event Detection In Computed Tomography (PREDICT)

Hiroshima University

Status: Unknown

Conditions: Coronary Artery Disease; Cardiovascular Diseases; Atherosclerosis

Study type: Observational

Funder types: Other

Identifiers

NCT00991835

PREDICT2009

Details and patient eligibility

About

Disruption of an atherosclerotic plaque is responsible for at least two-thirds of acute coronary syndrome. Thus, identification of plaques vulnerable to rupture has become important. The natural history of individual plaques is unknown and needs to be established. Multidetector computed tomography (MDCT) angiography is a useful noninvasive imaging modality for assessing coronary plaque characteristics. Using MDCT, the researchers prospectively investigate the relationship between the characterization of coronary plaques and cardiovascular events in a large multicenter study.

Enrollment: 3,015 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with known or suspected coronary artery disease.

Exclusion criteria

• irregular heart beat,
• known allergy towards the contrast agent,
• renal dysfunction,
• uncontrolled heart failure,
• previous coronary bypass surgery, or pacemaker or ICD implantation, ST elevation MI or unstable hemodynamic condition,
• impossible breath-hold, OR
• end-stage cancer.