Plaque Removal in Children Using Charcoal and Nylon Toothbrushes

Cairo University (CU)

Status: Begins enrollment this month

Conditions: Effectiveness of Charcoal-infused Versus Nylon Bristle Toothbrushes on Plaque Removal and Oral Bacterial Reduction in Children

Treatments: Device: soft charcoal infused bristle toothbrush (iLive) with bamboo handle; Device: soft nylon bristle toothbrush (Oral B JUNIOR 6-12)

Study type: Interventional

Funder types: Other

Identifiers

NCT07563400

CU-PD-RCT-CHARCOAL-2026

Details and patient eligibility

About

This study will compare two types of toothbrushes in children: a charcoal-infused bristle toothbrush and a regular nylon bristle toothbrush. We want to see which toothbrush is better at removing plaque and reducing bacteria in the mouth. Children will be randomly assigned to use one of the toothbrushes. We will measure the levels of bacteria in small samples of fluid taken from the gums to see if one toothbrush reduces harmful bacteria more than the other.

Full description

This study is a clinical trial designed to compare the effectiveness of two types of toothbrushes in children aged 6-10. One group of children will use a toothbrush with charcoal-infused bristles, while the other group will use a standard nylon bristle toothbrush. All children will be taught the same brushing technique and will brush their teeth twice daily for two minutes using a pea-sized amount of toothpaste.The study will last two weeks. Researchers will measure four times how much dental plaque is removed from each child's teeth, collect samples from the gums to examine bacteria, and test the toothbrush bristles for bacterial contamination by counting bacterial colonies.The goal is to determine which toothbrush is better at cleaning teeth and reducing harmful bacteria in the mouth.

Enrollment: 50 estimated patients

Sex: All

Ages: 6 to 10 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ● Children aged 6 to 10 years.

  • Medically free patients with no physical disability.
  • Patients must have proper oral hygiene.
  • Cooperative patients who will comply with follow-ups.
  • Parents who accept to sign informed consent.

Exclusion criteria

• ● Children with a medical condition or physical disability,

  • Children undergoing antibiotic treatment
  • Children with crowding, fixed or removable orthodontic appliances.
  • Children with pre-shedding mobile teeth were excluded from study.
  • Children who will be unable to attend follow-up visits.
  • Parents refuse to give written formed consent.
  • Presence of painful teeth.
  • Presence of active carious lesions

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Charcoal-Infused Bristle Toothbrush

Experimental group

Description:

Children in this arm will use a soft charcoal-infused bristle toothbrush twice daily for two minutes each time, using a pea-sized amount of fluoride-free toothpaste (Dabur Herb'l, India). Participants will be trained in the horizontal scrub technique and instructed on proper toothbrush storage to minimize bacterial contamination.

Treatment:

Device: soft charcoal infused bristle toothbrush (iLive) with bamboo handle

Nylon Bristle Toothbrush

Active Comparator group

Description:

Children in this arm will use a soft nylon bristle toothbrush twice daily for two minutes each time, using a pea-sized amount of fluoride-free toothpaste Participants will be trained in the horizontal scrub technique and instructed on proper toothbrush storage to minimize bacterial contamination.

Treatment:

Device: soft nylon bristle toothbrush (Oral B JUNIOR 6-12)