Plasma Cystatin C and Acute Kidney Injury

Jinhua Central Hospital

Status: Unknown

Conditions: Acute Kidney Injury

Study type: Observational

Funder types: Other

Identifiers

NCT01652755

N-H-Y

Details and patient eligibility

About

To evaluate the utility of plasma cystatin C(pCysC) as a predictive and diagnostic marker of acute kidney injury(AKI) in patients undergone cardiopulmonary bypass surgery.

Full description

This is a prospective AKI observational study in patients undergone cardiopulmonary bypass surgery. pCysC and plasma creatine will be measured at entry to ICU.AKI was defined as 50% increase in plasma creatine above baseline.The predictive and diagnostic performance of pCysC will be assessed from area under receiver operator characteristic curve(AUC) and odds ratio(OR).

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with CPB and admitted to ICU

Exclusion criteria

• patients with the age >80 or <18 years
• with preexisting renal dysfunction

Trial design

100 participants in 2 patient groups

AKI group

Description:

patients with AKI after cardiopulmonary bypass surgery

non-AKI group

Description:

patients without AKI during study period