Plasma exoRNA-Based Liquid Biopsy to Diagnose Clinically Significant Prostate Cancer

Air Force Military Medical University of People's Liberation Army

Status: Enrolling

Conditions: Clinically Significant Prostate Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT07492927

KY20262014-F-1

Details and patient eligibility

About

The aim of the present study is to investigate a plasma exosome RNA signature to diagnose clinically significant prostate cancer.

Enrollment: 1,700 estimated patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Blood prostate-specific antigen PSA>4ng/dl;
2. Patients suspected of having prostate cancer through clinical symptoms, digital rectal examination, ultrasound examination, magnetic resonance imaging.
3. The patient is willing to undergo prostate biopsy.

Exclusion criteria

1. Previous diagnosis of prostate cancer through prostate biopsy;
2. History of other malignant tumors in the past two years;
3. According to the research physician''s judgment, serious complications may occur and affect the normal conduct of the experiment

Trial design

1,700 participants in 1 patient group

Study Cohort

Description:

The experimental arm receiving diagnosis from serum RNA combination