Plasma Oxalate in Patient With Short Bowel (OXAGO)

Civil Hospices of Lyon

Status: Completed

Conditions: Hyperoxaluria; Short Bowel Syndrome; Hyperoxalemia

Treatments: Procedure: Pulse Wave Velocity (PWV) measurement; Biological: Blood sampling; Procedure: central pressure measurement; Biological: Urine sampling

Study type: Observational

Funder types: Other

Identifiers

NCT04119765

69HCL18_0408

Details and patient eligibility

About

Hyperoxaluria due to fat malabsorption is seen in patients suffering from short bowel and can lead to stones and nephrocalcinosis. Not all patients are prone to these renal complications. only urinary oxaluria is measured in practice. Plasma oxalate shouldn't increase theoretically in these patients. However recent report showed an increase of plasma oxalate in patient with enteric hyperoxaluria. The aim of this study is to assess the plasma oxalate distribution in this specific population to have a new tool to predict renal complication of these patients.

Enrollment: 47 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Type II short bowel for more than 6 months
• Affiliated to a social health care

Exclusion criteria

• Primary hyperoxaluria
• Other type of short bowel than type II
• Minor patient or major patient protected by the law