Plasma RBP Levels in Patients With Idiopathic Hypogonadotrophic Hypogonadism

Gulhane School of Medicine

Status: Completed

Conditions: Idiopathic Hypogonadotropic Hypogonadism

Treatments: Drug: Sustanon 250 mg ampule (Testosterone esters)

Study type: Observational

Funder types: Other

Identifiers

NCT01758094

24122012

Details and patient eligibility

About

The aim of the present study was to demonstrate the RBP4 levels, association of RBP4 with insulin resistance and influence of testosterone treatment on this cytokine in patients with idiopathic hypogonadotropic hypogonadism.

Enrollment: 25 patients

Sex: Male

Ages: 19 to 26 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

decreased serum testosterone concentration below the normal range (serum T < 300ng/dL), FSH and LH levels within or below the normal range, absence of a pituitary or hypothalamic mass lesions on MRI, presence of gonadotropin response to repetitive doses of GnRH, normal smell test and normal karyotypes

Exclusion criteria

previous androgen treatment, history of smoking, presence of bilateral anorchia, intellectual deficiency, diabetes mellitus, arterial hypertension or dyslipoproteinemia, medication of any kind and drug abuse. Because of possible confounding effects, patients with other hormone deficiencies were excluded.

Trial design

25 participants in 1 patient group

Hypogonadotropic hypogonadism patients

Description:

Treatment naive 25 patients with idiopathic hypogonadotrophic hypogonadism

Treatment:

Drug: Sustanon 250 mg ampule (Testosterone esters)