Plasma TMAO (Trimethylamine N-oxide) as a Predictive Marker in Coronary Disease Patients

Gdansk University of Physical Education and Sport

Status: Completed

Conditions: Coronary Disease

Treatments: Diagnostic Test: plasma samples collection

Study type: Observational

Funder types: Other

Identifiers

NCT03899389

DSRiK/10/2018

Details and patient eligibility

About

The primary aim of the current research project is to determine whether the TMAO concentration in the blood can serve as a prognostic indicator of myocardial infarction.

The hypothesis is that in patients with recent myocardial infarction, TMAO concentration in blood is higher than in patients undergoing scheduled coronarography.

Full description

To the study will be included volunteers - patients with stable angina (SA), who were scheduled for conventional coronary angiography, and patients with acute coronary syndrome (ACS) who were admitted to the hospital with chest pain and undergoing coronography surgery. Blood samples will be taken from volunteers once - before the coronography surgery by qualified medical personnel.

Enrollment: 600 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• diagnosed stable angina (SA) or acute coronary syndrome (ACS) and planned coronography

Exclusion criteria

• unconscious patient

Trial design

600 participants in 3 patient groups

Acute Coronary Syndrome (ACS)

Description:

Patients with STEMI or NSTEMI infarction, who were admitted to the hospital with chest pain.

Treatment:

Diagnostic Test: plasma samples collection

Stable Angina (SA)

Description:

Patients with stable angina who were scheduled for conventional coronary angiography.

Treatment:

Diagnostic Test: plasma samples collection

Control Group (CON)

Description:

Healthy control group responding by age and gender to examined groups.

Treatment:

Diagnostic Test: plasma samples collection