Plasma Vitamin and Homocysteine Levels and Thrombosis in Patients With Ph-negative MPNs

Istanbul University

Status: Completed

Conditions: Thrombosis

Study type: Observational

Funder types: Other

Identifiers

NCT01878916

HcyMPN

Details and patient eligibility

About

Hyperhomocysteinemia is a risk for thrombosis. Thrombosis is more frequent in myeloproliferative neoplasms (MPNs) than the normal population. In this study, we investigated the thrombosis incidence, the effects of plasma homocysteine levels on thrombosis, and the correlations between folate, cobalamin, pyridoxine and homocysteine levels in MPNs, and to compare these results with the healthy controls.

Full description

Thirty-one new or formerly diagnosed MPN patients who consecutively visitted our outpatient clinic, as well as 40 age and sex matched healthy controls were enrolled in this study.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Adult MPN patients and healthy controls who gave a written consent were included in the study.

Exclusion criteria

Exclusion criteria included not giving a written consent and using medications without an indication which may have an effect on plasma homocysteine and vitamin levels.