Platelet Enriched Plasma for Treatment of Interstitial Cystitis

Mansoura University

Status and phase: Unknown; Phase 2; Phase 1

Conditions: Interstitial Cystitis; Platelet Enriched Plasma; Bladder Pain Syndrome

Treatments: Biological: platelet enriched plasma

Study type: Interventional

Funder types: Other

Identifiers

NCT04118946

MS.19.03.540

Details and patient eligibility

About

A prospective randomized trial will be conducted aiming at evaluation the efficacy and safety of platelet enriched plasma for management of bladder pain syndrome .

Enrollment: 33 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with a diagnosis of interstitial cystitis/ Bladder painful Syndrome for more than 3 months will be enrolled

Exclusion criteria

• Patients with Anemia, blood disorders, history of pelvic irradiation, pelvic malignancy, and active urinary tract infection unless treated, vesical stone, gynecological disorders e.g. uterine fibroid and neurological disorders will be excluded. Patients less than 18 years old will not be allowed to participate.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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33 participants in 2 patient groups

intravesical instillation

Active Comparator group

Description:

Intravesical instillation of platelet enriched plasma every week for 6 weeks

Treatment:

Biological: platelet enriched plasma

submucosal injection

Active Comparator group

Description:

submucosal injectionof platelet enriched plasma

Treatment:

Biological: platelet enriched plasma